Annelotte van Bommel

69 Variation in immediate breast reconstruction Table 4. Univariate and multivariate analyses of factors determining the use of immediate breast reconstruction after mastectomy in 1,881 patients with ductal carcinoma in situ operated between 2011 and 2013 in the Netherlands. Univariate Analysis Multivariate Analyses n OR 95% CI OR 95% CI Age Below 50 265 2.29 1.79 - 2.93 2.29 1.79 - 2.94 50 to 65 452 ref ref 65 or above 69 0.16 0.12 - 0.22 0.17 0.13 - 0.22 Multifocal No 627 ref ref Yes 159 1.56 1.22 - 1.99 1.40 1.07 - 1.82 Grade 1 80 ref n.a. 2 271 0.89 0.64 - 1.25 n.a. 3 398 0.78 0.56 - 1.07 n.a. Unknown 37 0.83 0.49 - 1.39 n.a. CI, Confidence interval; OR, Odds Ratio. Figure 2. Funnel plot showing hospital differences in percentage of patient with ductal carcinoma in situ treated with mastectomy and immediate breast reconstruction, unadjusted (terra squares) and adjusted for age and multifocality (ocher triangles) (2011 – 2013). Observed Average 95%Cl Case-mixcorrected Number of patients undergoing a mastectomy for DCIS per hospital (2011-2013) Percentage of patients undergoing an immediate breast reconstruction 0 20 40 60 80 100 120 140 100% 90% 80% 70% 60% 50% 40% 30% 20% 10% 0% 4