Govert Veldhuijzen

144 Chapter 7 orientation, and content, which may improve the distractive effect ensuring an enhanced patient comfort and satisfaction. To achieve a maximal immersive effect, VR content must be developed which provides specific targeted distraction for colonoscopy, e.g., relaxing colors, relaxing music, and properly selected visualizations. CONCLUSION In summary, patients accept VR distraction undergoing colonoscopy, without compromising technical success of the procedure. Future studies are justified to evaluate the possible substitution of sedation with VR. Patients reported VR experience as pleasant and distracting, facilitating patient recruitment for these trials. ACKNOWLEDGEMENTS GV and NK carried out the trial, conceived the study, organized the design and coordination of the study and drafted the first version of this manuscript. AvE participated in the design and coordination of this study. JD supervised GV, RvW supervised NK, both participated in trial design and coordination. All authors read and approved the final manuscript. The authors would like to acknowledge dr. Fia Voogd (FV) and dr. Björn van Heumen (BvH) as the participating endoscopists in this trial. This pilot study is an investigator-initiated trial. The authors declare that they have no competing interests. The pilot study was funded by the Radboudumc.