Govert Veldhuijzen

70 Chapter 4 you have a computer/tablet/smart phone with internet access? (If not, do you have a peer who does?) We have the possibility to give you the information using an internet-based application. This is subject to our scientific research, comparing the novel method to a traditional visit of the outpatient’s clinic. If you cooperate in this trial, you will have to answer several questionnaires in the process. We also use information from your patient record. If you agree, we will randomize the method of education; either digital or nurse counselling. If no, reason for declining is noted. Negative answers are categorized in reasons to decline participation. If yes, can I have your e-mail address? 1.3. Randomize patients to the intervention or control group per center after obtaining permission. NOTE: This is linked to the invitation that is sent out; patients are asked for their e-mail addresses, linked to their patient identification number. The automated HTML script then randomly decides which invitation is being sent (nurse visit or computer-based education). The outcome is visible to the assistant. 1.4. Make sure that the patient reads the automatically sent email with instructions regarding more information on the trial. Here, digital informed consent for trial participation is obtained. 2. Baseline questionnaire 2.1. Subject the patient to the intervention or control group after randomization. Make sure that the patient completes the first questionnaire, containing baseline characteristics, several validated tools such as the RAND-36, PAM- 13, eHealth Literacy Scale and the STAI. 3. Intervention arm: patient is prepared with computer- based education 3.1. Make sure that the patient receives the interactive CBE via e-mail. NOTE: Current best practices are implemented in the design, including the use of plain language, good accessibility and obligatory interaction to engage users. 7 The used CBE is a web-based platform, mimicking the patient journey with specific video guided by voiceover, supported by photos, three-dimensional animation and instructive texts. 3.2. Conduct a dedicated video and photo shoot specific for each separate endoscopy unit in the trial following a uniform script. (Figure 2., the CBE used in one of the trial sites is accessible via https://trials.medify.eu/cbe-colonoscopy) . Divide the video in short clips, with a maximum duration of 45 seconds.