Govert Veldhuijzen

89 CBE is non-inferior to nurse counselling prior to colonoscopy, a multicenter RCT The control group was invited by mail to our outpatient clinic for a routine nurse counselling visit. The nurse explained the procedure in full, acquired the relevant information on sedation pre-assessment and handed out a short written leaflet on purgative use. 13 After completing either the CBE of nurse counselling, patients were scheduled for colonoscopy. Study design We used patient reported study questionnaires at several time points. (Figure 2.) At the first time point (T1), baseline demographic characteristics, previous experience with colonoscopy, patient satisfaction and validated questionnaires for eHealth literacy and patient productivity were recorded. 14,15 After receiving the patient education (either nurse counselling or CBE), the level of trait and state anxiety was measured. 16 On the day of colonoscopy, we collected patient information prior to colonoscopy (T2). Laxative use, the information re-call test and patient state anxiety were collected. Here, we also noted information on sickness absence leave. 15 In the CBE group, the need for additional contact moments was scored. The quality of the bowel preparation during colonoscopy was assessed by the Boston Bowel Preparation Scale (BBPS). 17 Colonoscopy specific data (indication, type of sedation and analgesic, ASA classification) were collected. Finally, prior to discharge (T3) patient satisfaction measures were recorded. 18 Endoscopy The attending endoscopists were blinded for the type of education patients received. All were familiarized or updated with the use of the BBPS before onset of the trial. The trial sites used either polyethylene glycol or sodium picosulfate-based standard split dose regimes for bowel preparation. 19 Outcomes The primary outcome of the trial was quality of bowel preparation as assessed with the BBPS. We recorded the need for repeat examinations due to inadequate BBPS. Secondary outcome measures were patient related outcome measures, including sickness absence leave, anxiety levels after instruction and prior to colonoscopy, satisfaction and information re-call. 5