Jacky Luiten

104 | Chapter 7 Figure 7.5 Trends in axillary treatment in breast conserving surgery. ALND = axillary lymph node dissection; SLNB = sentinel lymph node biopsy. Risk of invasive local recurrence For the period 1989 ‐ 2010, iRFS analysis comparing BCS with and without adjuvant radiotherapy showed a five ‐ year iRFS rate of 98.7% [CI 98.4% ‐ 99.0%] for women undergoing BCS with adjuvant radiotherapy, compared to 95.0% [CI 94.1% ‐ 95.8%] for women undergoing BCS only ( p <0.001; Figure 7.6a). The ten ‐ year iRFS rates were 96.6% [CI 96.2% ‐ 97.0%] vs. 90.2% [CI 89.0% ‐ 91.5%] respectively ( p <0.001). The fifteen ‐ year iRFS rate was 94.2% [93.6% ‐ 94.8%] compared to 87.1% [CI 85.6% ‐ 88.6%] respectively ( p <0.001). For the period 2011 ‐ 2018, the five ‐ year iRFS rate was 99.3% [CI 99.1% ‐ 99.5%] for women undergoing BCS with adjuvant radiotherapy, compared to 98.8% [CI 98.2% ‐ 99.4%] for women undergoing BCS only ( p = 0.01; Figure 7.6b).