Jacky Luiten

I gratefully acknowledge that the creation of this thesis was supported by Maastricht University, Elisabeth Tweesteden Ziekenhuis Tilburg, Bevolkings ‐ onderzoek regio Zuid, Integraal Kankercentrum Nederland, ABN AMRO, Agendia Inc., ChipSoft BV, Novart is Pharma BV, Pfizer and Surgipoort BV, owner of www.chirurgenoperatie.nl.