Jos Jansen

2 61 CCDC115 Deficiency Causes a Disorder of Golgi Homeostasis with Abnormal Protein Glycosylation Table S5. Quantification of transferrin IEF Family Individual 0-sialo (%) 1-sialo (%) 2-sialo (%) 3-sialo (%) 4-sialo (%) 5-sialo (%) 6-sialo (%) Control range (n=60) 0.0-3.2 0.0-5.0 3.3 -7.6 4.9 -10.6 47.3-62.7 18.7-31.5 3.2-7.8 F1 II1 2.25 7.57 ↑ 21.24 ↑ 29.27 ↑ 29.86 ↓ 7.88 ↓ 1.93 ↓ II2 3.42 ↑ 9.90 ↑ 19.69 ↑ 26.36 ↑ 27.49 ↓ 10.66 ↓ 2.48 ↓ II4 3.68 ↑ 8.57 ↑ 13.77 ↑ 17.03 ↑ 35.90 ↓ 17.35 ↓ 3.70 F2 II1* 1.86 4.60 13.67 ↑ 33.14 ↑ 42.85 ↓ 3.88 ↓ F3 II2 no data available F4 II1 2.4 6.3 ↑ 15.8 ↑ 24.6 ↑ 35.5 ↓ 12.6 ↓ 2.7 ↓ II2 no data available F5 II1 no data available * Transferrin isoforms were measured with HPLC