Sanne Hoeks

Chapter 2 30 REFERENCES 1. BILLINGHAM RE, BRENT L, MEDAWAR PB. Actively acquired tolerance of foreign cells. Nature . Oct 1953;172(4379):603-6. doi:10.1038/172603a0 2. Wang J, Zhan P, Ouyang J, Chen B, Zhou R, Yang Y. Unrelated donor umbilical cord blood transplantation versus unrelated donor bone marrow transplantation in adult and pediatric patients: A meta-analysis. Leuk Res . Aug 2010;34(8):1018-22. doi:10.1016/j.leukres.2009.11.020 3. Levy O. Innate immunity of the newborn: basic mechanisms and clinical correlates. Nat Rev Immunol . May 2007;7(5):379-90. doi:10.1038/nri2075 4. Bennett CL, Christie J, Ramsdell F, et al. The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat Genet . Jan 2001;27(1):20-1. doi:10.1038/83713 5. Lu L, Zhou X, Wang J, Zheng SG, Horwitz DA. Characterization of protective human CD4CD25 FOXP3 regulatory T cells generated with IL-2, TGF-β and retinoic acid. PLoS One . Dec 2010;5(12):e15150. doi:10.1371/journal. pone.0015150 6. Gottschalk RA, Corse E, Allison JP. TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo. J Exp Med . Aug 2010;207(8):1701-11. doi:10.1084/jem.20091999 7. Semple K, Nguyen A, Yu Y, Wang H, Anasetti C, Yu XZ. Strong CD28 costimulation suppresses induction of regulatory T cells from naive precursors through Lck signaling. Blood . Mar 2011;117(11):3096-103. doi:10.1182/ blood-2010-08-301275 8. Haxhinasto S, Mathis D, Benoist C. The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells. J Exp Med . Mar 2008;205(3):565-74. doi:10.1084/jem.20071477 9. Francisco LM, Salinas VH, Brown KE, et al. PD-L1 regulates the development, maintenance, and function of induced regulatory T cells. J Exp Med . Dec 2009;206(13):3015-29. doi:10.1084/jem.20090847

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