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182 Chapter 8 TABLE 1. Subject characteristics. Variable n (%) Catheter placement (direction) Antegrade Retrograde 9 (47) 10 (53) Placement method Interventional radiology Colonoscopy 16 (84) 3 (16) Response to bisacodyl Sensation (urge/pain/cramping) Stools 18 (95) 17 (89) Diagnostic workup Anorectal manometry (with positive RAIR) Rectal biopsy Contrast enema Colonic transit time MRI 19 (100) 8 (42) 14 (74) 8 (42) 5 (26) Surgery before colonic manometry Antegrade continence enemas Sacral nerve stimulation Ileostomy 11 (58) 1 (5) 2 (11) Surgery after colonic manometry Antegrade continence enemas Sacral nerve stimulation Ileostomy Resection 1 (5) 1 (5) 1 (5) 4 (21) Manometry data Long single motor patterns In most children (n=16, 84%) long single motor patterns were recorded, these contractions occurred in 12 children before the meal and in 15 children after the meal. Details on amplitude, velocity, length of propagation are provided in Table 2, together with previously published data acquired in children with FC using water-perfused colonic manometry. High-amplitude propagating contractions HAPCs were detected in four children (21%) in the preprandial phase, in five children (26%) in the post-prandial phase and in 16 children (84%) after administration of bisacodyl. Three out of four children with preprandial HAPCs also had postprandial HAPCs. Details on the characteristics of HAPCs are provided in Table 2.

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