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235 Treatment adherence 11 Medication diaries We received 86 completed medication diaries (75% of all included children). In 76/86 children (88%), all prescribed medication doses were reported to be taken. In five children (6%), one dose of medication was reportedly not taken, in all of these cases one daily dose was prescribed every day of the week and therefore these children had still received >80% of their prescribed weekly doses. In five children (6%), less than 80% of prescribed weekly doses of medication were reported to be taken. BMQ Details on beliefs about medication as evaluated with the BMQ are provided in Table 2. Only for the BMQ-Concerns scale, a statistically significant difference was found between adherent and nonadherent children; nonadherent children had higher scores, representing higher levels of parental concerns about their child’s medication. We found no statistically significant correlations between the BMQ subscales (including the Necessity-Concerns differential) and the MARS-5 score (Table 3). When comparing results from children and their parents, a statistically significant difference was found for BMQ-Overuse, with children reporting stronger beliefs about medication being overused (Supplemental file 2). B-IPQ Illness perceptions were evaluated with the B-IPQ, results are provided in Table 2. For the B-IPQ questions regarding treatment control (B-IPQ4) and emotions (B-IPQ8), statistically significant differences were found between adherent and nonadherent children (Table 2). Compared to parents of adherent children, parents of nonadherent children reported that the treatment was more important in controlling their child’s symptoms. Moreover, the emotional impact of a child’s FC symptoms on parents was negatively correlated with medication adherence. There was a statistically significant correlation between the B-IPQ8 (emotions) and the MARS-5 score (r s -0.192, P = .044)(Table 3). For five out of eight IPQ-questions, child-reported scores were significantly different from parental responses (Supplemental file 2). TSQM Results of the TSQM, which assessed satisfaction with treatment, are presented in Table 2. Parents of 21 children (18%) reported that their child experienced side effects from their treatment for FC, 19 of them completed the TSQM-questions regarding side effects sufficiently to calculate the TSQM-side effects score (Table 2). For the domains pertaining to convenience and satisfaction, statistically significant differences were found between adherent and nonadherent children (Table 2). Parents of nonadherent children reported that the treatment was less convenient and that they perceived less satisfaction regarding