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Nonpharmacologictreatmentsforchildhoodconstipation: systematic review. Pediatrics 2011;128(4):753–61. 12. Gordon M, Naidoo K, Akobeng AK, Thomas AG. Cochrane Review: Osmotic and stimulant laxatives for the management of childhood constipation (Review). Evid Based Child Health 2013;8(1):57–109. 13. Tabbers MM, Benninga MA. Constipation in children: fibre and probiotics. BMJ Clin Evid 2015;pii:303. 14. Kokke FTM, Scholtens PAMJ, Alles MS, et al. A dietary fiber mixture versus lactulose in the treatment of childhood constipation: a double-blind randomized controlled trial. J Pediatr Gastroenterol Nutr 2008;47(5):592–7. 15. Üstündağ G, Kuloğlu Z, Kirbaş N, Kansu A. Can partially hydrolyzed guar gum be an alternative to lactulose in treatment of childhood constipation? Turk J Gastroenterol 2010;21(4):360–4. 16. Chmielewska A, Horvath A, Dziechciarz P, Szajewska H. Glucomannan is not effective for the treatment of functional constipation in children: a double- blind, placebo-controlled, randomized trial. Clin Nutr 2011;30(4):462–8. 17. Weber TK, Toporovski MS, Tahan S, Neufeld CB, de Morais MB. Dietary fiber mixture in pediatric patients with controlled chronic constipation. J Pediatr Gastroenterol Nutr 2014;58(3):297–302. 18. Banaszkiewicz A, Szajewska H. Ineffectiveness of Lactobacillus GG as an adjunct to lactulose for the treatment of constipation in children: a double- blind, placebo-controlled randomized trial. J Pediatr 2005;146(3):364–9. 19. Tabbers MM, Chmielewska A, Roseboom MG, et al. Fermented milk containing Bifidobacterium lactis DN-173 010 in childhood constipation: a randomized, double- blind, controlled trial. Pediatrics 2011;127(6):e1392-9. 20. Koppen IJN, Di Lorenzo C, Saps M, et al. Childhood constipation: finally something is moving! Expert Rev Gastroenterol Hepatol 2016;10((1)):141–55. 21. Chmielewska A, Szajewska H. 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Guerra PVP, Lima LN, Souza TC, et al. Pediatric functional constipation treatment with Bifidobacterium-containing yogurt: a crossover, double-blind, controlled trial. World J Gastroenterol 2011;17(34):3916–21. 27. Khodadad A, Sabbaghian M. Role of synbiotics in the treatment of childhood constipation: a double-blind randomized placebo controlled trial. Iran J Pediatr 2010;20(4):387–92. 28. Kuizenga-Wessel S, Benninga MA, Tabbers MM. Reporting outcome measures of functional constipation in children from 0 to 4 years of age. J Pediatr Gastroenterol Nutr 2015;60(4):446–56. 29. Kuizenga-Wessel S, Heckert SL, Tros W, van Etten- Jamaludin FS, Benninga MA, Tabbers MM. Reporting on Outcome Measures of Functional Constipation in Children - A Systematic Review. J Pediatr Gastroenterol Nutr 2016;62(6):840–6. REFERENCES

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