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342 FUTURE PERSPECTIVES As a result of technological advances, the information that can be obtainedwithmanometry has become much more detailed over the past years. Until now, most commonly accepted assumptions have been based on evidence obtained with low resolution manometry and it is therefore likely that this vast increase of information will lead to a better understanding of colonic motility. However, since sample sizes of colonic manometry studies are generally small, it is important to strive for study designs that allow for comparison or pooling of data. In the future, collaborative study setups would therefore be helpful. The use of gastrointestinal neurostimulation has increased over the years, with several different treatment modalities gaining interest. SNS is one of those modalities and is discussed in this thesis. Two other noninvasive neurostimulation options that may gain popularity in the future are abdominal transcutaneous electrical stimulation (TES) and posterior tibial nerve stimulation (PTNS). TES uses interferential current, neurostimulation is delivered via surface electrodes arranged in a manner that crosses two currents within the abdomen. 51 Promising results of TES in the treatment of constipation have been described in the literature. 52–55 PTNS involves neurostimulation of the posterior tibial nerve at the level of the ankle, either percutaneously via a needle or transcutaneously via an electrode placed on the skin. 51 There is some degree of evidence for the benefit of PTNS in adults with defecation disorders, but evidence in children is very limited. 51 In the digital era that we live in, healthcare is expected to keep up with the rapid developments in society in future years. This will likely result in an increase of digital health solutions. In this thesis, we discussed how digital learning tools may be used to improve guideline awareness and adherence. Moreover, digital health solutions may also be deployed at the patient level, for example to improve treatment outcome and medication adherence. The utilization of apps for the purposes of parental education, pediatric lifestyle improvement and increasing treatment adherence is increasingly studied. 56–58 In the future, efforts should be made to develop an app supporting the management of children with FDDs in order to improve patient care.