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65 Functional constipation and overweight 2 Data were analyzed using independent samples t test, Pearson χ 2 , and Fisher exact test where appropriate using IBM SPSS Statistics for Windows v 22.0 (IBM Corporation Armonk, New York). When comparing the means of multiple groups, one-way ANOVA with post- hoc analyses applying Bonferroni corrections was used when there was the assumption of homogeneity of variance, the Games-Howell test was used when homogeneity of variance was not assumed. P -values of <.05 were considered statistically significant. FIGURE 1. Flowchart depicting inclusion process of the study. Other FGIDs, functional gastrointestinal disorders other than functional constipation. RESULTS In total, 2,820 children (51.7% boys) between 8 and 18 years of age were included; a flowchart of the inclusion process is depicted in the Figure 1. The mean age was 12.1 years (SD 2.3); 1,660 (58.9%) were school children between 8 and 12 years of age, and 1,160 (41.1%) were adolescents between 13 and 18 years of age. The majority of children (88.4%) attended public schools. The mean age of children in public schools was 12.3 years (SD 2.3) compared with 10.4 years (SD 1.6) in children attending private schools ( P < .01). The mean age of children differed significantly between regions ( P < .01); children in the Amazon region had a mean age of 13.5 years (SD 2.2), and they were significantly older than the rest of the children in the Andes (11.8 years of age, SD 2.4), the Atlantic region (12.0 years of age, SD 1.9), and the Pacific region (11.9 years of age, SD 2.4).

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