Bibian van der Voorn

129 EARLY LIFE GROWTH ON CORTISOL AFTER PREMATURITY FIGURE 1. Flowchart of STEP-1 and -2 Abbreviations: HM, human milk; PDF, postdischarge formula;TF, term formula CROSS SECTIONAL ANALYSES Birth weight SDS was positively associated with cortisol at 3 mo. and 6 mo. corrected age, β [95%CI]: 32.78 [8.74 to 56.81], P=0.01 and 20.90 [–0.35 to 42.14], P=0.05 respectively, and birth weight ≤–2 SDS was associated with lower cortisol compared to birth weight >–2 SDS at 6 mo. corrected age (–91.60 [–172.86 to –10.35], P=0.03). At 3 mo. corrected age, a non-significant association between cortisol and SGA-status was found (–49.83 [–105.85 to 6.19], P=0.08) ( Figure 2A and Table 3 ). At term age, cortisol was lower in SGA CUG– compared to AGA GR– infants (–115.69 [–212.06 to –19.31], P= 0.02). At 3 mo. corrected age, a non-significant association between cortisol and SGA CUG+ compared to AGA GR– was found (–62.40 [–133.03 to 8.23], P=0.08), and at 6 mo. corrected age, a non-significant association between cortisol and SGA CUG– compared to AGA GR– was found (–64.08 [–134.65 to 6.49], P=0.08) ( Figure 2B and Table 3 ).