Bibian van der Voorn

199 GENERAL DISCUSSION AND SUMMARY REFERENCES 1 Perined. Perinatale Zorg in Nederland 2015. (Utrecht, 2016). 2 De Kloet, E., Vreugdenhil, E., Oitzl, M. & Joels, M. Brain corticosteroid receptor balance in health and disease. Endocrine Reviews 19 , 269-301 (1998). 3 Raybaud, C., Ahmad,T., Rastegar, N., Shroff, M. & Al Nassar, M. The premature brain: developmental and lesional anatomy. Neuroradiology 55 Suppl 2 , 23-40 (2013). 4 Short, S. J. et al. Correspondence between hair cortisol concentrations and 30-day integrated daily salivary and weekly urinary cortisol measures. Psychoneuroendocrinology 71 , 12-18 (2016). 5 Xiang, L., Sunesara, I., Rehm, K. E. & Marshall, G. D., Jr. Hair Cortisol Concentrations Are Associated with Hair Growth Rate. Neuroimmunomodulation 23 , 287-294 (2016). 6 Hanson, M. A. & Gluckman, P. D. Early developmental conditioning of later health and disease: physiology or pathophysiology? Physiol Rev 94 , 1027-1076 (2014). 7 Barker, D. J. & Osmond, C. Infant mortality, childhood nutrition, and ischaemic heart disease in England and Wales. Lancet 1 , 1077-1081 (1986). 8 Sullivan, E. C., Hinde, K., Mendoza, S. P. & Capitanio, J. P. Cortisol concentrations in the milk of rhesus monkey mothers are associated with confident temperament in sons, but not daughters. Dev Psychobiol 53 , 96-104 (2011). 9 Vandenbroucke, J. P. When are observational studies as credible as randomised trials? The Lancet 363 , 1728-1731 (2004). 10 Taichman, D. B. et al. Data Sharing Statements for Clinical Trials - A Requirement of the International Committee of Medical Journal Editors. N Engl J Med 376 , 2277-2279 (2017). 11 Hollanders, J. J., van der Pal, S. M., van Dommelen, P., Rotteveel, J. & Finken, M. J. J. Growth pattern and final height of very preterm vs. very low birth weight infants. Pediatr Res (2017). 12 Greaves, R. F., Jevalikar, G., Hewitt, J. K. & Zacharin, M. R. A guide to understanding the steroid pathway: new insights and diagnostic implications. Clin Biochem 47 , 5-15 (2014). 13 Riepe, F. G., Mahler, P., Sippell, W. G. & Partsch, C. J. Longitudinal study of plasma pregnenolone and 17-hydroxypregnenolone in full-term and preterm neonates at birth and during the early neonatal period. J Clin Endocrinol Metab 87 , 4301-4306 (2002). 14 Kajantie, E. et al. Circulating glucocorticoid bioactivity in the preterm newborn after antenatal betamethasone treatment. J Clin Endocrinol Metab 89 , 3999-4003 (2004). 15 Peacock, J. L., Marston, L., Marlow, N., Calvert, S. A. & Greenough, A. Neonatal and infant outcome in boys and girls born very prematurely. Pediatr Res 71 , 305-310 (2012). 16 Stevenson, D. K. et al. Sex differences in outcomes of very low birthweight infants: the newborn male disadvantage. Arch Dis Child Fetal Neonatal Ed 83 , F182-185 (2000). 17 Hintz, S. R. et al. Gender differences in neurodevelopmental outcomes among extremely preterm, extremely-low- birthweight infants. Acta Paediatr 95 , 1239-1248 (2006). 18 Warris, L. T. et al. Hydrocortisone as an Intervention for Dexamethasone-Induced Adverse Effects in Pediatric Patients With Acute Lymphoblastic Leukemia: Results of a Double-Blind, Randomized Controlled Trial. J Clin Oncol 34 , 2287-2293 (2016). 19 Meijer, O. C. & de Kloet, E. R. A Refill for the Brain Mineralocorticoid Receptor: The Benefit of Cortisol Add-On to Dexamethasone Therapy. Endocrinology 158 , 448-454 (2017). 20 de Kloet, E. R., Claessens, S. E. & Kentrop, J. Context modulates outcome of perinatal glucocorticoid action in the brain. Front Endocrinol (Lausanne) 5 , 100 (2014). 21 Claessens, S. E. et al. Development of individual differences in stress responsiveness: an overview of factors mediating the outcome of early life experiences. Psychopharmacology (Berl) 214 , 141-154 (2011). 22 Conde-Agudelo, A. & Diaz-Rossello, J. L. Kangaroo mother care to reduce morbidity and mortality in low birthweight infants. Cochrane Database Syst Rev , CD002771 (2016).

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