Bibian van der Voorn

83 MILK GLUCOCORTICOID DIURNAL RHYTHMICITY Milk cortisol concentration, nmol/L 50 40 30 20 10 0 Time during the day, h 23:00 21:00 19:00 17:00 15:00 13:00 11:00 9:00 7:00 5:00 3:00 1:00 A 112 111 116 113 114 Page 1 Milk cortisone concentration, nmol/L 60 50 40 30 20 10 0 Time during the day, h 23:00 21:00 19:00 17:00 15:00 13:00 11:00 9:00 7:00 5:00 3:00 1:00 B 116 113 114 Page 1 Milk cortisone / (cortisol + cortisone) ratio 1,0 ,9 ,8 ,7 ,6 ,5 ,4 Time during the day, h 23:00 21:00 19:00 17:00 15:00 13:00 11:00 9:00 7:00 5:00 3:00 1:00 . 0. 0. 0. 0. 0. 0. C 112 116 FIGURE 2. Boxplots showing medians and ranges of concentrations of milk cortisol (A) and milk cortisone (B) and the cortisone-to- (cortisol + cortisone) ratio (C) over 24 h during week 4 postpartum (Study 2).The circles represent outliers and are labeled with their anonymized study number. n = 10 mothers and 92 milk samples.