Marieke van Rosmalen

Promotoren prof. dr. W.L. van der Pol prof. dr. J. Hendrikse Copromotoren dr. H.S. Goedee dr. ir. M. Froeling The research described in this thesis was supported by a grant of the Prinses Beatrix Spierfonds (W.OR17-21). Financial support by the Prinses Beatrix Spierfonds for the publication of this thesis is gratefully acknowledged.