Marieke van Rosmalen

Chapter 2 40 Supplemental table 2.2 Mean MRC grade per muscle group Examination site Total cohort (n = 100) Short disease duration (n = 50) Long disease duration (n = 50) p Arm Elbow flexion 4.4 4.5 4.3 0.63 Elbow extension 4.7 4.7 4.6 0.33 Shoulder abduction 4.5 4.5 4.5 0.38 Wrist flexion 4.4 4.5 4.3 0.63 Wrist extension 3.9 4.1 3.6 0.20 Hand Finger flexion 4.5 4.7 4.3 0.01 Finger extension 3.3 3.7 3.0 0.03 Finger spreading 3.1 3.5 2.7 0.03 Thumb adduction 3.4 3.9 2.9 0.01 Thumb abduction 3.0 3.6 2.4 0.01 Thumb opposition 3.2 3.7 2.7 0.03 Leg Hip flexion 4.9 4.8 4.9 0.33 Knee flexion 4.9 4.9 4.9 0.73 Knee extension 4.9 5.0 4.9 0.38 Foot Foot plantar flexion 4.3 4.8 3.9 0.03 Foot dorsal flexion 3.4 4.2 2.6 0.01 Toes flexion 4.2 4.7 3.7 0.03 Toes extension 3.5 4.1 2.9 0.04 Short disease duration is defined as disease duration < 180.6 months. Long disease duration is defined as disease duration ≥ 180.6 months. Abbreviations: MRC = Medical Research Council.