Daan Pieren

153 Regulatory KIR+RA+ CD8+ T cells accumulate with age A B T NAIVE T CM T EM T EMRA KIR + RA + NKG2A + RA + 0 1000 2000 3000 4000 Helios expression in subset (MFI) *** *** *** *** *** T NAIVE T CM T EM T EMRA KIR + RA + NKG2A + RA + 0 500 1000 1500 CD122 expression in subset (MFI) ** ********* *** Supplementary Figure 6. KIR + RA + T cells highly express Helios and CD122. Expression (MFI) of ( A ) Helios and ( B ) CD122 within each of the indicated CD8 + T-cell subsets in healthy individuals (20-82 years of age, n=50). Statistical significance of data presented in bar graphs (means ± s.d.) was determined using Friedman test (with Dunn’s post-test). (** p <0.01, *** p <0.001). 5