Daan Pieren

154 Chapter 5 Influenza B Rhinovirus A Seasonal Coronavirus RSV hMPV 0 +2 +8 Healthy 0 10 20 30 % KIR + RA + within CD8 + T cells ns Time after fever onset (weeks) 0 +2 +8 Healthy 0 10 20 30 40 50 % KIR + RA + within CD8 + T cells ns Time after fever onset (weeks) 0 +2 +8 Healthy 0 5 10 15 20 % KIR + RA + within CD8 + T cells Time after fever onset (weeks) ns 0 +2 +8 Healthy 0 20 40 60 % KIR + RA + within CD8 + T cells ns Time after fever onset (weeks) 0.0653 ns ns 0 +2 +8 Healthy 0 10 20 30 40 % KIR + RA + within CD8 + T cells 0.08 Time after fever onset (weeks) ns ns D Fever Cough Sore throat Nasal congestion Headache Difficulty breathing Myalgia 0 20 40 60 80 100 Time (days) B 63.70 11.00 10.60 1.67 T+0 T+2 T+8 Healthy CD69 (BV786) CD8 (BUV 395) C 2.55 4.71 4.26 T NAIVE T CM T EM 12.20 40.60 9.03 T EMRA KIR + RA + NKG2A + RA + CD69 (BV786) CD8 (BUV395) Influenza A Influenza A Supplementary Figure 7. Presence of KIR + RA + T cells during viral respiratory infection.