Daan Pieren

CO-EXPRESSION OF TIGIT AND HELIOS REFINES THE DEFINITION OF IMMUNOSENESCENT CD8 + T CELLS DURING AGING Daan K.J. Pieren 1 , Noortje A.M. Smits 1 , Rimke J. Postel 1 , Vinitha Kandiah 1 , Jelle de Wit 1 , Josine van Beek 1 , Debbie van Baarle 1,2 , Teun Guichelaar 1 . Manuscript in preparation 1 Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands 2 Center for Translational Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands