Maxime Verhoeven

199 Development and validation of DAS-OST Supplementary Figure S1 Bland-Altman plot for difference (DAS28 – DAS-OST) using data of internal validation cohort. Internal validation cohort consisted of 1120 observations fromMMC cohort, not used in development cohort. DAS-OST consisted of total OST-score, gender, ESR and VAS. Blue line= 0; Red line= mean of the difference; Red lines (dashed)= +/- 2SD of mean of the difference; Green line (dashed)= + 3SD of mean of the difference. Supplementary Figure S2 Bland-Altman plot for difference (DAS28 – DAS-OST(JC)) using data of internal validation cohort. Internal validation cohort consisted of 1120 observations fromMMC cohort, not used in development cohort. DAS-OST(JC) consisted of √JC-OST, gender, ESR and VAS. Blue line= 0; Red line= mean of the difference; Red lines (dashed)= +/- 2SD of mean of the difference; Green line (dashed)= + 3SD of mean of the difference. Supplementary Figure S3 Bland-Altman plot for difference (DAS28 – DAS-OST with- out VAS) using data of internal validation cohort. Internal validation cohort consisted of 1120 observations fromMMC cohort, not used in development cohort. DAS-OST without VAS consisted of total OST-score, gender and ESR. Blue line= 0; Red line= mean of the difference; Red line (dashed)= + 2SD of mean of the difference; Green line (dashed)= + 3SD of mean of the difference. 10

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