Maxime Verhoeven

211 DAS28 vs. DAS-OST; rheumatologist’s clinical classification SUPPLEMENTARY FILE Supplementary Data S1: Clinical classification To determine the clinical classification of a physician (or physician assistant), we decided to make two categories; active disease or inactive disease. Active is defined as: - The decision to start a new csDMARD / bDMARD / tsDMARD at present consultation - Increasing dose of the used DMARD - Intramuscular injection with glucocorticoid - When the treating rheumatologist described “Active disease” or used synonym terms Inactive is defined as: - Tapering the dose of csDMARD / bDMARD / tsDMARD, not because of adverse-effects - Stopping csDMARD / bDMARD / tsDMARD, not because of adverse-effects - When the treating rheumatologist described “remission” or used synonym terms One rheumatologist, AAAW, went cross-sectionally through the medical records of the participating patients to assess disease activity as active/inactive based on his clinical interpretation on the records. One of the inclusion criteria for participation was the availability of a DAS28 measurement, with, thereafter, a HandScan measurement, performed during the same clinical visit. In addition, only one unique visit per patient was included. Of the included medical records, a randomly drawn subset of 39 clinic visits was blindly re-assessed by two other rheumatologists, JT and JWGJ for testing agreement on this clinical interpretation, which was overall 92.5% with classifications of AAAW. 11