Mylène Jansen

104 Chapter 5 Supplementary Table S1 : Inclusion and exclusion criteria for the original randomized controlled trial Inclusion criteria Age <65 years Radiological joint damage: Kellgren and Lawrence score >2 (as indicated by orthopedic specialist) Intact knee ligaments Normal range of motion (minimum of 120 degrees flexion) Normal stability Body mass index <35 kg/m 2 Patients with medial tibiofemoral compartmental OA considered for HTO according to regular clinical practice Exclusion criteria Psychological inabilities or difficult to instruct Not able to undergo MRI examination (standard protocol) Inflammatory or rheumatoid arthritis present or in history Posttraumatic fibrosis due to fracture of the tibial plateau Bone-to-bone contact in the joint (absence of any joint space on radiograph) Surgical treatment of the involved knee Primary patellofemoral OA Mechanic varus axis deviation of more than 10 degrees Contralateral knee OA that needs treatment HTO: high tibial osteotomy; MRI: magnetic resonance imaging; OA: osteoarthritis.