Mylène Jansen

160 Chapter 8 Results Patients Before 2020, a total of 73 patients were treated with the latest distraction device, of whom 68 gave permission for use of their data. In 1 patient full treatment was not carried out (frame was removed within a week because of pain), while the other 67 patients received full KJD treatment. Of these, 34 patients used Iodosorb® during treatment, while the other 33 patients did not. The baseline characteristics of both groups are shown in Table 1, showing no significant differences between groups. There was no missing data. Table 1 : Baseline characteristics of knee joint distraction patients with or without cadexomer iodine (Iodosorb®) Without Iodosorb® (n=33) With Iodosorb® (n=34) P- value Age (years) 52.0 (7.0) 52.9 (7.6) 0.624 Male sex, n (%) 14 (42) 19 (56) 0.271* BMI (kg/m 2 ) 27.0 (3.0) 27.9 (2.8) 0.259 Diabetes mellitus, n (%) 1 (3) 1 (3) 0.983* Smoking status, n (%) - Never - Former - Current 20 (61) 12 (36) 1 (3) 19 (56) 14 (41) 1 (3) 0.921* Left leg, n (%) 11 (33) 16 (47) 0.252* Mean and standard deviation or n (%) are given. BMI: body mass index. P-values were calculated with independent t -tests or with chi-square tests for categorical variables (indicated with *). Infections The number of patients who experienced infections during and after treatment are shown in Table 2 for both groups. During treatment, patients who did not use Iodosorb® experienced twice as many infections as patients who used the ointment (64% versus 32%; p= 0.010). Table 2 : Infections during and after treatment with and without use of cadexomer iodine (Iodosorb®) during treatment. Without Iodosorb® (n=33) With Iodosorb® (n=34) P- value Patients with pin tract infections during treatment 21 (64) 11 (32) 0.010 Patients with >1 7-day antibiotics course 10 (30) 2 (6) 0.009 Patients with infections after treatment 2 (6) 3 (9) 0.667 N (%) is given. Bold p- values indicate statistical significance ( p< 0.05) calculated with chi-square tests. Also, there was a significant difference in the number of patients with more serious infections, requiring more antibiotics than the standard 7-day antibiotic prescription (30% without Iodosorb® versus 6% with Iodosorb®; p= 0.009). In all cases, the additional antibiotics consisted of multiple courses or 1 longer course of oral antibiotics; none of the patients required hospital admission or intravenous antibiotics during treatment.