Mylène Jansen

284 Chapter 14 Table 2 : Two-year changes in the 3 patient groups KJD HTO HTO KJD TKA KJD HTO vs HTO KJD HTO vs KJD TKA KJD TKA vs HTO Change Change Change Difference P d Difference P d Difference P d MAC ThCtAB (mm) -0.01 (-0.18 to 0.16) -0.12 (-0.22 to -0.02) 0.24 (0.08 to 0.39) 0.11 (-0.07 to 0.29) 0.225 0.36 -0.01 (-0.29 to 0.28) 0.954 0.76 -0.35 (-0.58 to -0.12) 0.004 1.22 LAC ThCtAB (mm) -0.07 (-0.15 to 0.00) -0.02 (-0.09 to 0.05) -0.01 (-0.12 to 0.10) -0.05 (-0.16 to 0.06) 0.351 0.28 -0.07 -0.25 to 0.11) 0.416 0.34 -0.02 (-0.18 to 0.14) 0.814 0.06 MAC dABp (%) 0.1 (-3.0 to 3.3) 3.4 (0.5 to 6.3) -7.7 (-12.9 to -2.5) -3.3 (-7.7 to 1.1) 0.142 0.44 3.6 (-4.3 to 11.5) 0.366 0.91 11.1 (4.2 to 18.0) 0.002 1.44 LAC dABp (%) 0.5 (0.2 to 0.8) 0.1 (-0.1 to 0.3) 0.1 (-1.2 to 1.4) 0.4 (0.1 to 0.8) 0.026 0.67 0.1 (-1.7 to 1.9) 0.903 0.23 -0.3 (-1.5 to 1.0) 0.678 0.02 Mean MAC JSW (mm) 0.31 (-0.11 to 0.74) 0.47 (0.14 to 0.79) 0.84 (0.24 to 1.43) -0.15 (-0.67 to -0.36) 0.547 0.18 -0.02 (-0.97 to 0.94) 0.969 0.51 -0.36 (-1.16 to 0.44) 0.374 0.37 Mean LAC JSW (mm) 0.22 (-0.63 to 1.06) -0.47 (-1.08 to 0.13) 0.15 (-0.36 to 0.66) 0.69 (-0.30 to 1.68) 0.167 0.42 0.08 (-1.26 to 1.41) 0.904 0.05 -0.62 (-1.75 to -0.50) 0.271 0.44 Changes and differences are shown with mean and 95% confidence interval. Bold p -values indicate statistical significance (p<0.05), for changes over time calculated with paired t -tests. Differences between groups and corresponding p -values were calculated with linear regression, correcting for statistically significantly different baseline characteristics. d : Cohen’s d ; dABp: percentage of denuded subchondral bone area; HTO: high tibial osteotomy; JSW: joint space width; KJD HTO : knee joint distraction (KJD) patients with indication HTO; KJD TKA : KJD patients with indication total knee arthroplasty; LAC: least affected compartment; MAC: most affected compartment; ThCtAB: mean cartilage thickness over the total subchondral bone area.