Mylène Jansen

286 Chapter 14 Table 4 : Differences in 2-year changes between groups based on osteoarthritis severity and treatment KJD mild vs KJD severe HTO mild vs HTO severe KJD mild vs HTO mild KJD severe vs HTO severe Difference P d Difference P d Difference P d Difference P d MAC ThCtAB (mm) 0.46 (0.22 to 0.70) <0.001 1.47 -0.02 (-0.23 to 0.19) 0.828 0.08 0.08 (-0.09 to 0.25) 0.332 0.40 -0.33 (-0.55 to -0.11) 0.005 1.09 MAC dABp (%) -8.7 (-16.0 to -1.4) 0.020 0.97 4.1 (-1.6 to 9.8) 0.154 0.52 -1.1 (-4.0 to 1.9) 0.459 0.31 10.5 (3.7 to 17.2) 0.003 1.13 Mean MAC JSW (mm) 0.75 (-0.11 to 1.60) 0.084 0.72 0.01 (-0.66 to 0.67) 0.985 0.01 0.42 (-0.07 to 0.91) 0.089 0.75 -0.25 (-1.02 to 0.52) 0.521 0.28 Differences are shown with mean and 95% confidence interval. Differences between groups and corresponding p- values were calculated with linear regression, correcting for statistically significantly different baseline characteristics; bold p- values indicate statistical significance ( p< 0.05). d : Cohen’s d ; dABp: percentage of denuded subchondral bone area; HTO: high tibial osteotomy; JSW: joint space width; KJD HTO : knee joint distraction (KJD) patients with indication HTO; KJD TKA : KJD patients with indication total knee arthroplasty; LAC: least affected compartment; MAC: most affected compartment; ThCtAB: mean cartilage thickness over the total subchondral bone area.