Mylène Jansen

372 Chapter 17 Supplementary Table S3 : Baseline and 1-year Altman scores for patients with synovial fluid aspirations Baseline 1 year P- value Medial femur (0–3) 2.0 (0.5) 2.1 (1.1) 0.075 Lateral femur (0–3) 2.0 (1.0) 2.0 (1.5) 0.500 Medial tibia (0–3) 2.0 (0.8) 2.0 (0.8) 0.401 Lateral tibia (0–3) 1.0 (1.3) 1.0 (1.7) 0.260 Total (0–12)* 6.7 (2.0) 6.9 (1.8) 0.653 Median and interquartile ranges are given and p- values are calculated with Wilcoxon Signed Rank tests. *For the total Altman score, the mean and standard deviation are given and the p- value is calculated with a paired t -tests. Supplementary Table S4 : Pearson correlations between baseline total Altman score and TGF β -1 and IL-6, and between 1-year changes Baseline values Total Altman TGF β -1 IL-6 Total Altman 1 R= -0.380 p= 0.147 R= 0.209 p= 0.422 TGF β -1 R= -0.380 p= 0.147 1 R= 0.130 p= 0.632 IL-6 R= 0.209 p= 0.422 R= 0.130 p= 0.632 1 One-year changes ΔTotal Altman ΔTGF β -1 ΔIL-6 ΔTotal Altman 1 R= 0.305 p= 0.289 R= 0.299 p= 0.280 ΔTGF β -1 R= 0.305 p= 0.289 1 R= -0.438 p= 0.118 ΔIL-6 R= 0.299 p= 0.280 R= -0.438 p= 0.118 1 The row and column with thicker borders indicate the relevant correlations. IL-6: interleukin-6; TGF β -1: transforming growth factor- β 1.

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