Mylène Jansen

42 Chapter 2 Supplementary Figure S8 : Change in visual analogue score (VAS) of pain compared between knee joint distraction (KJD) and total knee arthroplasty (TKA) and between KJD and high tibial osteotomy (HTO), both 1 and 2 years after treatment. References can be used multiple times because of division in patient cohort. CI: confidence interval; SD: standard deviation. Supplementary Figure S9 : Change in total Knee injury and Osteoarthritis Outcome Score (KOOS) compared between knee joint distraction (KJD) and total knee arthroplasty (TKA) and between KJD and high tibial osteotomy (HTO), both 1 and 2 years after treatment. References can be used multiple times because of division in patient cohort. CI: confidence interval; SD: standard deviation. Supplementary Figure S10 : Change in mean joint space width (JSW), compared between knee joint distraction (KJD) and high tibial osteotomy (HTO) at 1 and 2 years after treatment, between KJD and the untreated osteoarthritis initiative (OAI) cohort at 5 years after baseline, and between patients treated with KJD, microfracture and debridement and patients treated with microfracture and debridement alone after 4–7 years. For Aly 2011, p- values were used to calculate standard deviations (SD); for KJD the reported p- value of p< 0.000 was assumed to be p= 0.0001. CI: confidence interval; SD: standard deviation.