Mylène Jansen

Two-year results of KJD compared with HTO and TKA 65 4 Results Over the 2 years of follow-up, in the KJD TKA group, 1 patient was lost to follow-up after undergoing TKA surgery because of unsatisfactory clinical benefit (after 9 months). In the TKA group, 4 patients withdrew consent before surgery and 2 patients were lost to follow-up due to comorbidities discovered after treatment. In the KJD HTO group, 1 patient was excluded before surgery due to inoperability and 2 patients were lost to follow-up after undergoing a TKA and HTO because of unsatisfactory treatment benefit (both after 12 months). In the HTO group, 1 patient was excluded before treatment due to anxiety and 4 patients were lost to follow-up because of comorbidities interfering with follow-up but unrelated to the procedure. Of the remaining 114 patients (out of the original 129), the baseline characteristics are presented in Table 2. Table 2 : Baseline characteristics of patients from the 2 randomized controlled trials KJD vs TKA KJD vs HTO KJD TKA (n=19) TKA (n=34) KJD HTO (n=20) HTO (n=41) Male sex, n (%) 8 (42) 12 (35) 15 (75) 24 (58) BMI (kg/m 2 ) 27.1 (3.8) 28.4 (6.0) 27.4 (3.3) 27.1 (3.3) Age (years) 55.7 (7.4) 55.4 (6.0) 51.2 (5.8) 49.3 (6.3) Leg axis (degrees) 2.1 (7.0) 2.8 (6.2) 5.9 (2.7) 6.1 (2.2) Kellgren-Lawrence grade, (median, IQR) - Grade 0, n (%) - Grade 1, n (%) - Grade 2, n (%) - Grade 3, n (%) - Grade 4, n (%) 4 (1.0) 0 (0) 0 (0) 1 (5) 8 (42) 10 (53) 3 (0.0) 0 (0) 0 (0) 7 (21) 21 (62) 6 (18) 3 (1.8) 0 (0) 5 (25) 4 (20) 10 (50) 1 (5) 3 (1.0) 1 (2) 4 (10) 11 (27) 21 (51) 4 (10) Flexion (degrees) 121 (10.5) 123 (7.7) 130 (7.2) 132 (8.5) Total WOMAC (0–100) 39.2 (15.6) 44.7 (20.6) 52.5 (20.5) 46.5 (19.6) Total KOOS (0–100) 38.4 (9.2) 35.8 (11.6) 45.7 (14.4) 40.6 (12.8) VAS pain (100–0) 63.8 (19.0) 71.9 (15.7) 52.3 (22.1) 64.7 (17.9) EQ-5D (0–1) 0.66 (0.25) 0.61 (0.24) 0.70 (0.20) 0.72 (0.18) ICOAP Combined (100–0) 57.7 (12.0) 64.9 (17.2) 54.2 (16.3) 58.5 (15.1) SF-36 PCS (0–100) 33.6 (9.0) 31.3 (7.2) 37.7 (6.7) 35.8 (8.1) SF-36 MCS (0–100) 54.5 (8.4) 54.0 (9.8) 55.0 (8.2) 55.1 (8.5) Minimum JSW (mm) 0.65 (1.3) - 0.49 (0.7) 0.54 (1.0) Mean JSW (mm) 1.93 (2.0) - 1.99 (1.5) 1.89 (1.2) Mean and standard deviation are given unless otherwise indicated. BMI: body mass index; EQ-5D: EuroQol-5D; HTO: high tibial osteotomy; ICOAP: Intermittent and Constant Osteoarthritis Pain score; IQR: interquartile range; JSW: joint space width; KJD HTO : KJD patients from the KJD versus HTO trial; KJD TKA : knee joint distraction patients from the KJD versus TKA trial; KOOS: Knee injury and Osteoarthritis Outcome Score; MSC: mental component scale; PCS: physical component scale; SF-36: Short Form 36; TKA: total knee arthroplasty; VAS: Visual Analogue Scale; WOMAC: Western Ontario and McMaster Universities Osteoarthritis Index.