Margriet Kwint

Outcome of treatment of synchronous oligometastases 55 3 Four out of six patients, who did not receive local therapy for the metastasis, had brain metastases which were considered too small for stereotactic radiotherapy after response to systemic therapy. The other 2 patients (1 liver and 1 bone metastasis) had a complete response after systemic treatment for the metastasis and only received radical treated for the primary tumor. Further treatment characteristics of the treatment of the metastases are shown in Table 3 . Table 1: patients and tumor characteristics. WHO = world health organization, NOS: not otherwise specified. TNM7 th edition was used for staging. * within brackets number of metastasis. Patient and tumor characteristics N (%) Sex Male 48 (52.7%) Female 43 (47.3%) WHO performance status 0 44 (48.4%) 1 45 (49.5%) 2 2 (2.2%) Stage (ignoring M-status) 1A 10 (11.0%) 1B 3 (3.3%) 2A 11 (12.1%) 2B 10 (11.0%) 3A 33 (36.3%) 3B 24 (26.4%) T-stage T0-Tx 2 (2.2%) T1 24 (26.4%) T2 33 (36.3%) T3 14 (15.4%) T4 18 (19.8%) Nodal stage N0 32 (35.2%) N1 10 (11.0%) N2 33 (36.3%) N3 16 (17.6%) Pathology Adenocarcinoma 58 (63.7%) Squamouscellcarcinoma 9 (9.9%) Large cell neuro-endocrine carcinoma 6 (6.6%) Non-small-cell lung cancer NOS 18 (19.8%) Number metastases 1 77 (84.6%) 2 9 (9.9%) 3 2 (2.2%) 4 3 (3.3%)