Margriet Kwint

Chapter 3 56 Patient and tumor characteristics N (%) Location metastases Brain (1)* 29 (31.9%) Brain (2) 3 (3.3%) Brain (3) 1 (1.1%) Brain (4) 3 (3.3%) Bone 23 (25.3%) Bone (2) 1 (1.1%) Adrenal gland 13 (14.3%) Lymph node 6 (6.6%) Liver 2 (2.2%) Soft tissue 1 (1.1%) Pulmonary 1 (1.1%) Thyroid Gland 1 (1.1%) Breast 1 (1.1%) Liver and bone 1 (1.1%) Pleural and bone 1 (1.1%) Brain and bone 1 (1.1%) Adrenal gland and pulmonary 1 (1.1%) Adrenal gland and brain 1 (1.1%) Adrenal gland (2) and lymph node 1(1.1%) Table 2: treatment characteristics of the primary tumor and lymph nodes. RT= Radiotherapy, * 1 patient with an occult primary tumor and 1 patient with complete response after targeted therapy of the primary tumor. Treatment primary tumor and lymph nodes N (%) Local treatment Radiotherapy 81 (89.0%) Radiotherapy only conventional RT 3 Radiotherapy only stereotactic RT 7 Sequential + conventional RT 56 Sequential + stereotactic RT 4 Concurrent fulldose +conventional RT 3 Concurrent lowdose + conventional RT 6 Targeted therapy + conventional RT 1 Targeted therapy + stereotactic RT 1 Surgery 8 (8.8%) Lobectomy 5 Segment resection 1 Sequential chemo + lobectomy 2 Systemic only* 2 (2.2%) Targeted therapy 1 Chemotherapy 1