Joeky Senders

56 Chapter 3 Of the 5699 patients that were identified in the NSQIP registry 2012-2015 with data on reoperation and associated reasons, 72 (1.3%) developed an ICH requiring surgical evacuation at a median of two days after surgery (IQR 0-8 days) (Fig 1e). ICH was the most common reason for reoperation (18.5% of the total number of reoperations). The median length of stay among ICH patients was 12 days (IQR 6-21 days) compared to four days (IQR 3-8 days) in non-ICH patients (Fig. 1f). The 55 patients (77.5%) that developed an ICH during the initial hospital stay, were discharged at a median of ten days (IQR 6-19) after the occurrence of ICH. TABLE 2. Multivariable analysis comparing risk profiles for deep venous thrombosis and pulmonary embolism occurring in-hospital versus post-discharge. Predictors In-hospital DVT Post-discharge DVT OR 95% CI p OR 95% CI p Age per 10 years increase 1.28 1.06-1.55 0.01 1.28 1.12-1.47 <0.001 BMI per 5 kg/m 2 increase 1.23 1.01-1.46 0.03 1.25 1.09-1.41 <0.001 Dependent functional status 2.63 1.18-5.27 0.01 0.82 0.34-1.68 0.62 Preoperative WBC >12000/µL 1.76 1.00-2.97 0.05 1.05 0.69-1.57 0.80 Steroid usage 1.38 0.71-2.52 0.32 2.17 1.39-3.30 <0.001 Admission ≥2 days before OR 1.85 1.08-3.19 0.02 2.02 1.37-2.98 <0.001 OR time per 60 min increase 1.26 1.13-1.39 <0.001 1.04 0.94-1.15 0.40 Predictors In-hospital PE Post-discharge PE OR 95% CI p OR 95% CI p Age per 10 years increase 1.08 0.84-1.41 0.56 1.33 1.13-1.58 <0.001 Male gender 0.93 0.43-2.04 0.85 2.32 1.38-4.07 0.002 BMI per 5 kg/m 2 increase 1.27 0.97-1.62 0.07 1.24 1.04-1.46 0.01 Dependent functional status 5.46 1.96-13.12 <0.001 2.15 0.94-4.31 0.05 OR time per 60 min increase 1.24 1.06-1.43 0.004 1.10 0.98-1.23 0.10 Abbreviations: BMI=body mass index; DVT=deep venous thrombosis; min=minutes; OR=operation room; PE=pulmonary embolism; WBC=white blood cell count. Multivariable analysis Older age and higher BMI were found to be risk factors of VTE overall (Tables 2-3). Dependent functional status and longer operative times were predictive for hospital VTE, but not for post-discharge events. Admission two or more days before surgery was a predictor of DVT, but not for PE. Steroid usage was predictive for post-discharge DVT, and male gender was predictive for post-discharge PE. Higher ASA-classification,