Joeky Senders

57 Venous thromboembolism en intracranial hemorrhage hypertension, weight loss, bleeding disorders, preoperative sodium < 135 mEq/L, and longer operative times were found to be predictors of postoperative ICH requiring surgical evacuation (Table 4). TABLE 3. Overview overall and specific risk factors for VTE. Overall risk factors - Older age - Higher BMI Specific risk factors In-Hospital Post-Discharge DVT - Admission ≥2 days pre-op - Longer operative times - Dependent functional status - Admission ≥2 days pre-op - Steroid usage PE a - Longer operative times - Dependent functional status - Male gender Abbreviations: BMI=body mass index; DVT=deep venous thrombosis; PE=Pulmonary embolism; pre-op=preoperatively; VTE=venous thromboembolism. a This study was underpowered to identify specific risk factors of in-hospital PEs. TABLE 4. Multivariable logistic regression analysis for ICH within 30 days after surgery. Predictor Definition ICH OR 95% CI p ASA-classification I-II Ref. - - III 1.45 0.74-3.11 0.31 IV-V 3.23 1.50-7.59 0.004 Hypertension 2.27 1.38-3.75 0.001 Weight loss 4.42 1.48-10.67 0.003 Bleeding disorder 3.13 1.16-7.09 0.01 Preoperative SIRS 2.45 0.98-5.21 0.05 Preoperative sodium 135-145 Ref. - - <135 2.41 1.29-4.26 0.004 >145 1.14 0.06-5.59 0.90 Operative time minutes 1.20 a 1.07-1.33 <0.001 Abbreviations: ASA=American Society of Anesthesiologists, CI=confidence interval, ICH=intracranial hemorrhage; SIRS = systematic inflammatory response syndrome. a Inflated β-coefficients to odds ratio per 60 minutes increase