Arjen Lindenholz

118 CHAPTER 5 Reliability study and vessel wall lesion distribution The calculated agreements for the number and location of the detected vessel wall lesions were as follows: ICC of 0.93 (95% CI; 0.90-0.96) and a DSC of 0.81. The Bland-Altman plot with 95% levels of agreement is shown in Figure 2 . Figure 2. Bland-Altman plot shows the level of agreement in the number of detected vessel wall lesions between two readers. Differences in detected vessel wall lesions are plotted against the mean number of detected vessel wall lesions of both readers. The blue line represents the mean of differences; the two red lines reflect the 95% limits of agreement. SD, standard deviation. Of the 90 participants included in this analysis, 60 had ischemic stroke (right MCA, n = 30; left MCA, n = 28; right ACA, n = 1; left ACA, n = 1); 25 had cerebral TIA (right- sided, n = 13); and five had transient monocular blindness (right-sided, n = 2). A total of 372 vessel wall lesions were found in 76 participants (84%); 135 of those lesions were enhancing. In 34 of the 60 participants with an ischemic stroke, 67 vessel wall lesions (18%) were detected in the vessels before the vascular comprised area or in the vascular territory itself, 33 of which were enhanced (49%). An example of a participant with multiple vessel wall lesions is shown in Figure 3 . More examples of intracranial vessel wall lesions are shown in Figure 4 . The numbers of vessel wall lesions according to arterial segment are shown in Supplemental Table 1 .