Arjen Lindenholz

143 Intracranial Atherosclerotic Burden and Cerebral Parenchymal Changes at 7T MRI 6 Figure 2: A 72-year-old female with a right-sided ischemic stroke; imaging 25 days after symptom onset. ( A-D ) Precontrast 7T transverse FLAIR images and ( E-H ) postcontrast 7T transverse T 1 -weighted MPIR-TSE vessel wall images. Lacunar infarcts are located in the right frontal (arrow in A ) and right frontotemporal area (arrow in B ). Multiple cortical microinfarcts are also seen (arrows in C ), as well as periventricular and deep white matter hyperintensities (arrows in D ). Note also the extensive enlarged periventricular spaces in this patient (not scored; arrows in E and F ). Vessel wall lesions are seen in the left and right middle cerebral arteries (M1 segments) (arrows in G and H ). In the secondary analyses, we did not find an association between intracranial vessel wall lesion burden and the number of cerebral parenchymal changes of any type ( Table 3 ). In the sub analyses, an association was found between the enhancing vessel wall lesion burden and the number of cortical microinfarcts (relative risk, 1.48; 95% CI, 1.04-2.11), but no other association was found between the enhancing vessel wall lesion burden and either presence ( Table 4 ) or number ( Table 5 ) of cerebral parenchymal changes.