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36 Chapter 2 Table 4. (continued) Instrument Study Study population Psychometrics Methodological quality Diagnoses N Age (Y) COSMIN property Results Rating COSMIN boxes* 1 Rating of results* 2 Modified Hammersmith Functional Motor Scale (MHFMS) (O’Hagen et al., 2007) SMA type II and III 38 Construct validity Correlation between HMFSE type II-III and GMFM/ functional rating score r= .97 / .90 Poor + 17 Correlation between HMFSE type III and GMFM/ functional rating score r= .94 / .88 Poor + Lower extremity physical functioning and mobility skills (LE85) (Gorton et al., 2010) Spastic CP 308 2-20 Measurement error The LE85 had good correlation with the Paediatric Outcomes Data Collection Instrument, Functional Independence Measure for Children, Gillette Functional Assessment Questionnaire, and Paediatric Quality of Life Inventory – CPmodule (range r=.63–.86). Good + 170 Construct validity Correlation between LE85 and FAQ walking scale r=.82, 95%CI .77-.87, p<.0001 Excellent + 90 Correlation between LE85 and average score 22-item skill set r=-.86, 95%CI -.8 to -.91, p<.0001 Good + 176 Correlation between LE85 and PODCI r=.85, 95%CI .81-.89, p<.0001 Excellent + 120 Correlation between LE85 andWeeFIM r=.83, 95%CI .77-.88, p<.0001 Excellent +