Gersten Jonker

COLOPHON Cover design: James Jardine | www.jamesjardine.nl Layout: James Jardine | www.jamesjardine.nl Print: Ridderprint | www.ridderprint.nl ISBN: 978-94-6416-488-6 De uitgave van dit proefschrift is mede ondersteund door de Nederlandse Vereniging voor Medisch Onderwijs en de Divisie Vitale Functies, UMC Utrecht. Copyright © 2021 by Gersten Jonker. All rights reserved. Any unauthorized reprint or use of this material is prohibited. No part of this thesis may be reproduced, stored or transmitted in any form or by any means, without written permission of the author or, when appropriate, of the publishers of the publications.