Matt Harmon

106 Chapter five Figure 2 . Laboratory parameters over time in volunteers with endotoxemia and fever and volunteers with endotoxemia treated with induced normothermi Lipopolysaccharide was given to all volunteers at T=0. Cooling to normothermia (37°C) was initiated at T=1 in the normothermia group. Dashed line indicates volunteers in the fever group. Solid line indicates volunteers in the normothermia group. Grey box represents the period of induced normothermia. Figure 2A: Data are represented as medians with bars representing the interquartile ranges. Figure 2B-F: Dots represent means with bars representing standard deviation. *P<0.05, N.S. = Not significant. Abbreviations: CRP= C-reactive protein, LPS = lipopolysaccharide