Matt Harmon

107 Chapter five Figure 3 . Shivering and thermal discomfort scores of volunteers during the study period. Figure 3A: shows the cumulative frequency of observed shivering scores during the study period. Grey bars show the fever group. White bars show the normothermia group. Figure 3B: shows the warmth and cold discomfort scored over time. Dots represent means with bars representing standard deviation. Lipopolysaccharide was given to all volunteers at T=0. Cooling to normothermia (37°C) was initiated at T=1 in the normothermia group. Dashed line indicates volunteers in the fever group. Solid line indicates volunteers in the normothermia group. Abbreviations: LPS = lipopolysaccharide