Matt Harmon

124 Chapter six Figure 2 . DIC scores in volunteers with endotoxemia and fever and volunteers with endotoxemia treated with induced normothermia. Figure 2A shows DIC scores over time. Lipopolysaccharide was given to all volunteers at T=0. Cooling to normothermia (37°C) was initiated at T=1 in the normothermia group. Grey box in figure 2A represents the period of induced normothermia. The dashed line represents the fever group and the solid line represents the normothermia group. Data are presented medians with bars representing the interquartile ranges. Figure 2B shows the frequency of DIC scores in both groups over all timepoints. *P<0.05, N.S. = Not significant. Abbreviations: DIC = Disseminated intravascular coagulation.