Matt Harmon

162 Chapter eight Table 1. Patient baseline characteristics Demographic characteristics Total no. N= 869 Age – years (mean, s.d.) 63.9 ± 12.2 Male sex no. (%) 707 (81.4) Background no. (%) Chronic heart failure 55 (6.3) TIA or stroke 69 (8.0) Arterial hypertension 347 (40.1) Asthma/COPD 86 (9.9) Diabetes mellitus 128 (14.8) Previous PCI 101 (11.6) Previous CABG 82 (9.5) Cardiac arrest characteristics Bystander witnessed arrest no. (%) 783 (90.1) Bystander CPR no. (%) 638 (73.4) Shock on admission no. (%) 111 (12.8) Prehospital intubation no. (%) 576 (67.2) Time to ROSC (min) (mean s.d.) 30.4 ± 21.7 Characteristics on admission pH 7.21 ± 0.15 PaCO 2 (kPa) (mean, s.d.) 6.4 ± 2 PaO 2 (kPa) (mean, s.d.) 25.1 ± 17 Lactate (mmol/L) (mean, s.d.) 6.5 ± 4.3 BE ≥ -5 (mmol/l) no. (%) 579 (7.3) GCS – Motor 1 no. (%) 443 (51.3) Sedated on arrival no. (%) 254 (29.4) SD = Standard deviation. TIA = transient ischemic attack. COPD = Chronic obstructive pulmonary disease. PCI = Percutaneous coronary intervention. CABG = Coronary artery bypass graft. GCS = Glasgow coma scale. ROSC = return of spontaneous circulation. PaCO 2 = arterial carbon dioxide pressure. PaO 2  = arterial oxygen pressure. kPa = kilopascal. CPR = cardiopulmonary resuscitation. BE = Base excess. Table 2. Number of missing measurements at each time point. Total no. N = 869 Time (h) T -1 0 4 12 20 28 32 36 Missing n 45 154 94 91 118 117 135 124 % of total 5.18 17.7 10.8 10.4 13.6 13.5 15.5 14.2 n = numbers. h = hours. T -1 = time at admission, after ROSC but before randomization.