Matt Harmon

182 Chapter nine Table 1. Baseline characteristics in patients with and without an infection All N=696 No confirmed infection N=518 Confirmed infection N=178 P-value Demographic characteristics Age (yr) - mean ±SD 64.0 ±12.0 64.2 ±12.0 63.4 ±12.1 0.43 Weight (kg) - mean ±SD 81.9 ±15.4 82.1 ±16.0 81.6 ±13.9 0.671 Male sex – no. (%) 568 (82) 425 (82) 143 (80) 0.659 Medical History - no.(%) Chronic heart failure 43 (6) 30 (6) 13 (5) 0.711 Previous AMI 144 (21) 102 (20) 42 (22) 0.531 Ischemic heart disease 191 (28) 140 (28) 51 (27) 1 Previous cardiac arrhythmia 110 (16) 81 (16) 29 (16) 0.906 Previous cardiac arrest 15 (2) 10 (2) 5 (3) 0.772 Arterial hypertension 272 (39) 193 (38) 79 (42) 0.331 TIA or stroke 50 (7) 41 (8) 9 (5) 0.183 Diabetes 108 (16) 78 (15) 30 (16) 0.811 Asthma or COPD 73 (11) 47 (9) 26 (14) 0.088 Immunodeficiency 24 (3) 9 (5) 15 (3) 0.168 Characteristics of the cardiac arrest Bystander performed CPR - no. (%) 503 (73) 369 (73) 134 (72) 0.856 Time from cardiac arrest to ROSC - median (IQR) 32 (22-50) 25 (16-39) 25 (18.5-40) 0.15 First monitored rhythm - no. (%) 0.176 Asystole - no. (%) 78 (11) 60 (12) 18 (10) - Non-perfusing VT - no. (%) 14 (2) 11 (2) 3 (2) - PEA - no. (%) 49 (7) 40 (8) 9 (5) - ROSC after bystander defibrillation - no. (%) 12 (2) 8 (2) 4 (2) - VF - no. (%) 530 (76) 254 (72) 242 (92) - Unknown - no. (%) 13 (2) 6 (1) 7 (4) - Clinical characteristics on admission First Body temperature (°C) - mean ±SD 35.3 ±1.2 35.3 ±1.2 35.4 ±1.1 0.313 Circulatory shock - no. (%) 75 (11) 58 (11) 17 (9) 0.404 SOFA score - mean ±SD 10.4 ±2.6 10.4 ±2.6 10.6 ±2.5 0.479 Abbreviations: AMI, acute myocardial infarction, BLS, basic life support, CPR, cardiopulmonary resuscitation, COPD, chronic obstructive pulmonary disease, IQR, interquartile range, PEA, pulseless electrical activity, ROSC, return of spontaneous circulation , SD, standard deviation, SOFA, sequential organ failure assessment , TIA, transient ischemic attack, VT, ventricular tachycardia, VF, ventricular fibrillation.