Matt Harmon

193 Chapter nine Supplemental Table 3. Baseline characteristics in patients treated with TTM33 vs. TTM36 TTM33 N=350 TTM36 N=346 P-value Demographic characteristics Age (yr) - mean ±SD 65.5 (11.7) 63.5 (12.3) 0.258 Weight (kg) - mean ±SD 82.6 (15.9) 81.3 (14.9) 0.703 Male sex – no. (%) 293(84) 275 (79) 0.182 Medical History - no.(%) Prior cardiovascular disease 216 (62) 204 (59) 0.494 Asthma or COPD 32 (9) 41 (12) 0.266 Characteristics of the cardiac arrest Bystander performed CPR - no. (%) 309 (88) 310 (90) 0.928 Time from cardiac arrest to ROSC – median (IQR) 25 (17-40) 25 (15-39.8) 0.469 Clinical characteristics on admission First Body temperature (°C) - mean ±SD 35.2 (1.2) 35.3 (1.1) 0.148 Circulatory shock - no. (%) 39 (11) 36 (10) 0.806 Abbreviations: CPR, cardiopulmonary resuscitation, COPD, chronic obstructive pulmonary disease, IQR, interquartile range, ROSC, return of spontaneous circulation, SD, standard deviation, TTM, targeted temperature management Supplemental Table 4. Microbiological characteristics of confirmed pneumonia and bacteremia in TTM33 vs TTM36 TTM33 (N=350) TTM36 (N=346) P-value Pneumonia, n (% of TTM patients) 81 (23) 77 (22) 1 GPC 20 (25) 20 (26) - GNC 35 (43) 32 (42) - PMF 31 (25) 31 (24) - Fungus 1 (1) 1 (1) - Bacteremia, n (% of TTM patients) 14 (4) 14 (4) 0.53 GPC 6 (43) 8 (57) - GNC 5 (36) 5 (36) - PMF 3 (21) 1 (7) - Fungus 0 (0) 0 (0) - Abbreviations: GNC, gram negative culture, GPC, gram positive culture, PMF, poly microbial flora. Percentages of cultures are relative to total amount of patients with pneumonia or bacteremia, unless stated otherwise.