Matt Harmon

196 Chapter nine Supplemental Table 8. Baseline characteristics in patients receiving antibiotic prophylaxis vs no antibiotic prophylaxis No antibiotic prophylaxis N=351 Antibiotic Prophylaxis N=345 P-value Demographic characteristics Age (yr) - mean ±SD 65.2 (12.2) 62.79 (11.8) 0.01 Weight (kg) - mean ±SD 80.1 (16) 83.8 (14.7) 0.002 Male sex – no. (%) 274 (78) 294 (85) 0.014 Medical History - no.(%) Chronic heart failure 22 (6) 21 (6) 1 Previous AMI 81 (23) 63 (18) 0.138 Ischemic heart disease 115 (33) 76 (22) 0.004 Previous cardiac arrhythmia 61 (17) 49 (14) 0.261 Previous cardiac arrest 11 (3) 4 (1) 0.121 Arterial hypertension 162 (46) 110 (32) 0.001 TIA or stroke 26 (8) 24 (7) 0.87 Diabetes 59 (17) 49 (14) 0.361 Asthma or COPD 46 (13) 27 (8) 0.031 Immunosuppression 9 (3) 17 (5) 0.118 Characteristics of the cardiac arrest Bystander performed CPR - no. (%) 249 (71) 254 (74) 0.399 Time from cardiac arrest to BLS - median (IQR) 1 (0-3) 0 (0-2) <0.0001 Time from cardiac arrest to ROSC - median (IQR) 26 (18-42) 24 (15-36) 0.004 First monitored rhythm - no. (%) 0.013 Asystole - no. (%) 54 (15) 24 (7) - Non-perfusing VT - no. (%) 6 (2) 8 (2) - PEA - no. (%) 23 (7) 26 (8) - ROSC after bystander defibrillation - no. (%) 6 (2) 6 (2) - VF - no. (%) 254 (72) 276 (80) - Unknown - no. (%) 8 (2) 5 (1) - Clinical characteristics on admission First Body temperature (°C) - mean ±SD 35.3 (1.1) 35.3 (1.6) 0.758 Circulatory shock - no. (%) 45 (13) 30 (9) 0.08 SOFA score - mean ±SD 10.6 (2.7) 10.3 (2.4) 0.183 Abbreviations: AMI, acute myocardial infarction, BLS, basic life support, CPR, cardiopulmonary resuscitation, COPD, chronic obstructive pulmonary disease, IQR, interquartile range, PEA, pulseless electrical activity, ROSC, return of spontaneous circulation , SD, standard deviation, SOFA, sequential organ failure assessment, TIA, transient ischemic attack, VT, ventricular tachycardia, VF, ventricular fibrillation.