Matt Harmon

21 Chapter one References 1 Peres Bota, D., Lopes Ferreira, F., Melot, C. & Vincent, J. L. Body temperature alterations in the critically ill. Intensive care medicine 30 , 811-816, doi:10.1007/s00134-004-2166-z (2004). 2 Walter, E. J., Hanna-Jumma, S., Carraretto, M. & Forni, L. The pathophysiological basis and consequences of fever. Critical care 20 , 200, doi:10.1186/s13054-016-1375-5 (2016). 3 M garbane, B., Axler, O., Chary, I., Pompier, R. & Brivet, F. G. Hypothermia with indoor occurrence is associated with a worse outcome. Intensive care medicine 26 , 1843-1849, doi:10.1007/s001340000702 (2000). 4 Ablordeppey, E. A. et al. Diagnostic Accuracy of Central Venous Catheter Confirmation by Bedside Ultrasound Versus Chest Radiography in Critically Ill Patients: A Systematic Review and Meta- Analysis. Crit Care Med 45 , 715-724, doi:10.1097/CCM.0000000000002188 (2017). 5 Callaway, C. W. et al. Part 8: Post-Cardiac Arrest Care: 2015 American Heart Association Guidelines Update for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation 132 , S465-482, doi:10.1161/CIR.0000000000000262 (2015). 6 Schortgen, F. et al. Fever control using external cooling in septic shock: a randomized controlled trial. American journal of respiratory and critical care medicine 185 , 1088-1095, doi:10.1164/rccm.201110-1820OC (2012). 7 Itenov, T. S. et al. Induced hypothermia in patients with septic shock and respiratory failure (CASS): a randomised, controlled, open-label trial. Lancet Respir Med 6 , 183-192, doi:10.1016/S2213- 2600(18)30004-3 (2018). 8 Mackowiak, P. A., Wasserman, S. S. & Levine, M. M. A critical appraisal of 98.6 degrees F, the upper limit of the normal body temperature, and other legacies of Carl Reinhold August Wunderlich. JAMA : the journal of the American Medical Association 268 , 1578-1580 (1992). 9 Niven, D. J. & Laupland, K. B. Pyrexia: aetiology in the ICU. Critical care 20 , 247, doi:10.1186/s13054- 016-1406-2 (2016). 10 Evans, S. S., Repasky, E. A. & Fisher, D. T. Fever and the thermal regulation of immunity: the immune system feels the heat. Nat Rev Immunol 15 , 335-349, doi:10.1038/nri3843 (2015). 11 Saper, C. B. & Breder, C. D. The neurologic basis of fever. The New England journal of medicine 330 , 1880-1886, doi:10.1056/NEJM199406303302609 (1994). 12 Tatro, J. B. Endogenous antipyretics. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 31 Suppl 5 , S190-201, doi:10.1086/317519 (2000). 13 Launey, Y., Nesseler, N., Malledant, Y. & Seguin, P. Clinical review: fever in septic ICU patients-- friend or foe? Critical care 15 , 222, doi:10.1186/cc10097 (2011). 14 Rice, P. et al. Febrile-range hyperthermia augments neutrophil accumulation and enhances lung injury in experimental gram-negative bacterial pneumonia. Journal of immunolog y 174 , 3676-3685 (2005). 15 Hasday, J. D. et al. Febrile-range hyperthermia augments pulmonary neutrophil recruitment and amplifies pulmonary oxygen toxicity. The American journal of patholog y 162 , 2005-2017 (2003). 16 Wang, W. C. et al. Fever-range hyperthermia enhances L-selectin-dependent adhesion of lymphocytes to vascular endothelium. Journal of immunolog y 160 , 961-969 (1998). 17 Small, P. M., Tauber, M. G., Hackbarth, C. J. & Sande, M. A. Influence of body temperature on bacterial growth rates in experimental pneumococcal meningitis in rabbits. Infection and immunity 52 , 484-487 (1986). 18 Saxena, M. et al. Early temperature and mortality in critically ill patients with acute neurological diseases: trauma and stroke differ from infection. Intensive care medicine 41 , 823-832, doi:10.1007/ s00134-015-3676-6 (2015).

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