Matt Harmon

62 Chapter three References 1 Angus, D. C. & van der Poll, T. Severe sepsis and septic shock. The New England journal of medicine 369 , 840-851, doi:10.1056/NEJMra1208623 (2013). 2 Levy, M. M. et al. 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Intensive care medicine 29 , 530-538, doi:10.1007/s00134-003-1662-x (2003). 3 Clemmer, T. P. et al. Hypothermia in the sepsis syndrome and clinical outcome. The Methylprednisolone Severe Sepsis Study Group. Crit Care Med 20 , 1395-1401 (1992). 4 Kushimoto, S. et al. The impact of body temperature abnormalities on the disease severity and outcome in patients with severe sepsis: an analysis from a multicenter, prospective survey of severe sepsis. Critical care 17 , R271, doi:10.1186/cc13106 (2013). 5 Marik, P. E. & Zaloga, G. P. Hypothermia and cytokines in septic shock. Norasept II Study Investigators. North American study of the safety and efficacy of murine monoclonal antibody to tumor necrosis factor for the treatment of septic shock. Intensive care medicine 26 , 716-721 (2000). 6 Arons, M. M. et al. Effects of ibuprofen on the physiology and survival of hypothermic sepsis. Ibuprofen in Sepsis Study Group. Crit Care Med 27 , 699-707 (1999). 7 Pajkrt, D. et al. Attenuation of proinflammatory response by recombinant human IL-10 in human endotoxemia: effect of timing of recombinant human IL-10 administration. Journal of immunolog y 158 , 3971-3977 (1997). 8 Leon, L. R., Kozak, W., Rudolph, K. & Kluger, M. J. An antipyretic role for interleukin-10 in LPS fever in mice. The American journal of physiolog y 276 , R81-89 (1999). 9 Leon, L. R. Hypothermia in systemic inflammation: role of cytokines. Frontiers in bioscience : a journal and virtual library 9 , 1877-1888 (2004). 10 Drewry, A. M., Fuller, B. M., Skrupky, L. P. & Hotchkiss, R. S. The Presence of Hypothermia Within 24 Hours of Sepsis Diagnosis Predicts Persistent Lymphopenia. Crit Care Med , doi:10.1097/ CCM.0000000000000940 (2015). 11 Mallet, M. L. Pathophysiology of accidental hypothermia. QJM 95 , 775-785 (2002). 12 Romanovsky, A. A., Shido, O., Sakurada, S., Sugimoto, N. & Nagasaka, T. Endotoxin shock: thermoregulatory mechanisms. The American journal of physiolog y 270 , R693-703 (1996). 13 Scicluna, B. P. et al. A Molecular Biomarker to Diagnose Community-acquired Pneumonia on Intensive Care Unit Admission. American journal of respiratory and critical care medicine 192 , 826-835, doi:10.1164/rccm.201502-0355OC (2015). 14 Klein Klouwenberg, P. M. et al. Interobserver agreement of Centers for Disease Control and Prevention criteria for classifying infections in critically ill patients. Crit Care Med 41 , 2373-2378, doi:10.1097/CCM.0b013e3182923712 (2013). 15 Garner, J. S., Jarvis, W. R., Emori, T. G., Horan, T. C. & Hughes, J. M. CDC definitions for nosocomial infections, 1988. American journal of infection control 16 , 128-140 (1988). 16 Calandra, T., Cohen, J. & International Sepsis Forum Definition of Infection in the, I. C. U. C. C. The international sepsis forum consensus conference on definitions of infection in the intensive care unit. Crit Care Med 33 , 1538-1548 (2005). 17 Bellomo, R. et al. Acute renal failure - definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Critical care 8 , R204-212, doi:10.1186/cc2872 (2004). 18 Force, A. D. T. et al. Acute respiratory distress syndrome: the Berlin Definition. JAMA : the journal of the American Medical Association 307 , 2526-2533, doi:10.1001/jama.2012.5669 (2012). 19 Peres Bota, D., Lopes Ferreira, F., Melot, C. & Vincent, J. L. Body temperature alterations in the critically ill. Intensive care medicine 30 , 811-816, doi:10.1007/s00134-004-2166-z (2004).