Matt Harmon

63 Chapter three 20 van Vught, L. A. et al. Reduced Responsiveness of Blood Leukocytes to Lipopolysaccharide Does not Predict Nosocomial Infections in Critically Ill Patients. Shock 44 , 110-114, doi:10.1097/ SHK.0000000000000391 (2015). 21 Tiruvoipati, R. et al. Hypothermia predicts mortality in critically ill elderly patients with sepsis. BMC geriatrics 10 , 70, doi:10.1186/1471-2318-10-70 (2010). 22 Laupland, K. B. et al. Severe hypothermia increases the risk for intensive care unit-acquired infection. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 54 , 1064-1070, doi:10.1093/cid/cir1033 (2012). 23 Nerad, J. L. et al. Interleukin-1 beta (IL-1 beta), IL-1 receptor antagonist, and TNF alpha production in whole blood. J Leukoc Biol 52 , 687-692 (1992). 24 Sakr, Y. et al. Being Overweight Is Associated With Greater Survival in ICU Patients: Results From the Intensive Care Over Nations Audit. Crit Care Med 43 , 2623-2632, doi:10.1097/ CCM.0000000000001310 (2015). 25 Steiner, A. A. & Romanovsky, A. A. Leptin: at the crossroads of energy balance and systemic inflammation. Prog Lipid Res 46 , 89-107, doi:10.1016/j.plipres.2006.11.001 (2007). 26 Saper, C. B. Neurobiological basis of fever. Annals of the New York Academy of Sciences 856 , 90-94 (1998). 27 Hoogendijk, A. J. et al. Plasma fractalkine is a sustained marker of disease severity and outcome in sepsis patients. Critical care 19 , 412, doi:10.1186/s13054-015-1125-0 (2015). 28 Sung, M. J. et al. Protective effect of alpha-lipoic acid in lipopolysaccharide-induced endothelial fractalkine expression. Circulation research 97 , 880-890, doi:10.1161/01.RES.0000186522.89544.4D (2005).