Matt Harmon

Chapter four 85 (A). Volcano plot (integrating adjusted p-values and fold expression indices) of gene expression differences in hypothermic septic patients compared to febrile patients in a cohort matched for APACHE IV scores and shock. Red dots, high expression genes; blue dots, low expression genes. (B) Unsupervised heatmap representation of the 205 significantly altered genes. (C) Bar plot showing high expression genes significantly associated with Ingenuity’s canonical signaling pathways in hypothermia compared to fever.