Matt Harmon

Chapter four 90 References 1 Young, P. J. et al. Early peak temperature and mortality in critically ill patients with or without infection. Intensive care medicine 38 , 437–444, doi:10.1007/s00134-012-2478-3 (2012). 2 Clemmer, T. P. et al. Hypothermia in the sepsis syndrome and clinical outcome. The Methylprednisolone Severe Sepsis Study Group. Crit Care Med 20 , 1395-1401 (1992). 3 Kushimoto, S. et al. The impact of body temperature abnormalities on the disease severity and outcome in patients with severe sepsis: an analysis from a multicenter, prospective survey of severe sepsis. Critical care 17 , R271, doi:10.1186/cc13106 (2013). 4 Romanovsky, A. A. et al. Fever and hypothermia in systemic inflammation: recent discoveries and revisions. Frontiers in bioscience : a journal and virtual library 10 , 2193-2216 (2005). 5 Steiner, A. A., Fonseca, M. T. & Soriano, F. G. Should we assume that hypothermia is a dysfunction in sepsis? Critical care 21 , 8, doi:10.1186/s13054-016-1584-y (2017). 6 Corrigan, J. J., Fonseca, M. T., Flatow, E. A., Lewis, K. & Steiner, A. A. Hypometabolism and hypothermia in the rat model of endotoxic shock: independence of circulatory hypoxia. J Physiol 592 , 3901-3916, doi:10.1113/jphysiol.2014.277277 (2014). 7 Wiewel, M. A. et al. Risk factors, host response and outcome of hypothermic sepsis. Critical care 20 , 328, doi:10.1186/s13054-016-1510-3 (2016). 8 Marik, P. E. & Zaloga, G. P. Hypothermia and cytokines in septic shock. Norasept II Study Investigators. North American study of the safety and efficacy of murine monoclonal antibody to tumor necrosis factor for the treatment of septic shock. Intensive care medicine 26 , 716-721 (2000). 9 Arons, M. M. et al. Effects of ibuprofen on the physiology and survival of hypothermic sepsis. Ibuprofen in Sepsis Study Group. Crit Care Med 27 , 699-707 (1999). 10 Drewry, A. M., Fuller, B. M., Skrupky, L. P. & Hotchkiss, R. S. The Presence of Hypothermia Within 24 Hours of Sepsis Diagnosis Predicts Persistent Lymphopenia. Crit Care Med , doi:10.1097/ CCM.0000000000000940 (2015). 11 van der Poll, T., van de Veerdonk, F. L., Scicluna, B. P. & Netea, M. G. The immunopathology of sepsis and potential therapeutic targets. Nat Rev Immunol 17 , 407-420, doi:10.1038/nri.2017.36 (2017). 12 Klein Klouwenberg, P. M. et al. Interobserver agreement of Centers for Disease Control and Prevention criteria for classifying infections in critically ill patients. Crit Care Med 41 , 2373-2378, doi:10.1097/CCM.0b013e3182923712 (2013). 13 van Vught, L. A. et al. Incidence, Risk Factors, and Attributable Mortality of Secondary Infections in the Intensive Care Unit After Admission for Sepsis. JAMA : the journal of the American Medical Association 315 , 1469-1479, doi:10.1001/jama.2016.2691 (2016). 14 Garner, J. S., Jarvis, W. R., Emori, T. G., Horan, T. C. & Hughes, J. M. CDC definitions for nosocomial infections, 1988. American journal of infection control 16 , 128-140 (1988). 15 Calandra, T., Cohen, J. & International Sepsis Forum Definition of Infection in the, I. C. U. C. C. The international sepsis forum consensus conference on definitions of infection in the intensive care unit. Crit Care Med 33 , 1538-1548 (2005). 16 Levy, M. M. et al. 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Intensive care medicine 29 , 530-538, doi:10.1007/s00134-003-1662-x (2003). 17 Peres Bota, D., Lopes Ferreira, F., Melot, C. & Vincent, J. L. Body temperature alterations in the critically ill. Intensive care medicine 30 , 811-816, doi:10.1007/s00134-004-2166-z (2004). 18 Scicluna, B. P. et al. A Molecular Biomarker to Diagnose Community-acquired Pneumonia on Intensive Care Unit Admission. American journal of respiratory and critical care medicine 192 , 826-835, doi:10.1164/rccm.201502-0355OC (2015). 19 Scicluna, B. P. et al. Classification of patients with sepsis according to blood genomic endotype: a prospective cohort study. Lancet Respir Med 5 , 816-826, doi:10.1016/s2213-2600(17)30294-1 (2017).

RkJQdWJsaXNoZXIy ODAyMDc0